PAPER Kurz A, Perneczky R
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Deb holmes
United States
Michel Goedert
MRC Laboratory of Molecular BiologyCambridge
PAPER Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, Wölfing H, Chieng BC, Christie MJ, Napier IA, Eckert A, Staufenbiel M, Hardeman E, Götz J
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.
Cell. 2010 Aug 6;142(3):387-97. Epub 2010 Jul 22 PubMed.PI(3,4,5)P 3
ANTIBODY monoclonal manufacturer Cat# Z-P345b immunogen = synthetic PtdIns(3,4,5)P 3 conjugated to BSA liquid, purified, PBS, diluted reacts primarily with the head group of the inidicated phosphoinositide; low cross reactivity with other phosphoinositides or phos
PI(3,4,5)P 3
ANTIBODY monoclonal manufacturer Cat# Z-P345 immunogen = synthetic PtdIns(3,4,5)P 3 conjugated to BSA liquid, affinity purified, PBS<br />Also available FITC or Biotin or HRP conjugated recognizes PtdIns(3,4,5)P 3; cross less than 1% with other Phosphatidyli
PI(3,4,5)P 3
ANTIBODY monoclonal manufacturer Cat# Z-A345 immunogen = synthetic PtdIns(3,4,5)P 3 conjugated to BSA liquid, ascites, thimerosal recognizes PtdIns(3,4,5)P 3; cross less than 1% with other Phosphatidylinositol phosphates or lipids IgM Second Messengers Echelon Bio
Susmita Halder
Manipal College of Medical SciencesIndia
Monalisa Chaudhury
India
Akihiko Takashima on Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse
COMMENT In this manuscript, Ittner and colleagues showed that tau has a role in Aβ toxicity, which may be different from the role of tau on microtubules. Interaction of tau and Fyn is required for stabilizing the NR2/PSD95 complex. Reduction of tau, or interferin
Lennart Mucke on Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at Synapse
COMMENT I am very enthusiastic about the paper by Ittner et al. for several reasons. First, it confirms the highly protective effects of tau reduction we observed in hAPP-J20 mice (Roberson et al., 2007 and Palop et al., 2007) in another APP transgenic line with
TNFα (L-19)
ANTIBODY polyclonal manufacturer Cat# sc-1351<br />Reference: <br /><a href="/papers/diabetes-accelerated-memory-dysfunction-cerebrovascular-inflammation-and-abeta-deposition" target="_new">Takeda, S, 2010</a> immunogen
IL-6 (M-19)
ANTIBODY polyclonal manufacturer Cat# sc-1265<br />Also available as rabbit, sc-1265-R<br />Reference: <br /><a href="/papers/diabetes-accelerated-memory-dysfunction-cerebrovascular-inflammation-and-abeta-deposition" target="_ne
PECAM-1 (TLD-3A12)
ANTIBODY monoclonal TLD-3A12 manufacturer Cat# 555025 immunogen = Lewis rat microglia Aqueous buffered solution, azide detects PECAM-1, 130 kDa IgG<sub>1</sub>,κ CD_ except CD11b, CD40, CD45 and CD147 BD Pharmingen Mouse Porcine Rat PECAM-1 http://alzf
Joana Oliveira
Portugal